Rosetta@Home
Описание
Определение трехмерной формы белков. Исследования в конечном итоге могут привести к нахождению лекарства для лечения таких болезней, как ВИЧ, малярия, рак и болезнь Альцгеймера.
Характеристики
Поддерживаемые платформы
Команды Беларуси
Скриншоты
RSS новости
- Project News Jan 29, 2012
Journal post from David BakerLast year we described in Science magazine the design of a new enzyme which catalyzes a chemical reaction called the Diels Alder reaction involving the formation of two carbon-carbon bonds. This reaction is interesting because no natural enzymes are known to catalyze the reaction. However, it wasn't a very good enzyme, and we asked FoldIt players to try to improve it. As described in Nature Biotechnology this month, remarkably FoldIt players were able to make the designed enzyme 20 times faster by inserting a completely new loop which helps the enzyme bind the chemicals it links together. The combination of Rosetta@Home and FoldIt is turning out to be powerful indeed for solving challenging problems in biomedicine!
- Project News Jan 16, 2012
Journal post from David BakerIn response to requests from many of you, we will be posting descriptions of the many scientific problems currently being tackled with Rosetta@Home on the Science message boards in the next couple of weeks--stay tuned! I also want to describe a new research direction we are now embarking on aimed at future cancer therapies. There are a small set of proteins which are frequently found at much higher levels than normal on the surface of cancer cells. We are starting to design small proteins which bind tightly to these tumor cell markers. If we are successful, we have collaborators who will be testing these proteins for their ability to target cancer cell killing agents to the tumors.
- Project News Jan 13, 2012
Rosetta@Home software updated to version 3.20. This should fix the graphical issues some users were seeing with version 3.19.
- Project News Jan 02, 2012
The hardware hosting the Rosetta@Home project is being moved from one
datacenter to another on the UW campus. We are using this disruption to update the sagging,
aging gear that runs the project. All of this will result in a few days of down time. We
will work to keep the outage to a minimum, but you migh want to grab enough work for a 4-5
day period. We appreciate your patience, interest and continued contributions to our
research. -KEL
